Anisotropic crystal growth of carbamazepine form I and a hydroxysulfonamide

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Comparison of the four anhydrous polymorphs of carbamazepine and the crystal structure of form I.

For decades, carbamazepine (CBZ) has served as a model compound for groups engaged in the study of crystal polymorphism. Despite considerable effort, crystal structures for only three of its four anhydrous forms have previously been determined. Herein, we report the first single crystal X-ray structure of the high temperature modification of CBZ (form I). Form I crystallizes in a triclinic cell...

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Form IV of carbamazepine.

Carbamazepine has been found to crystallize as a new polymorph that is stable at room temperature. We report the crystal structure of this C-centered monoclinic form (space group C2/c, cell parameters: a = 26.609, b = 6.9269, c = 13.957, beta = 109.702), which consists of hydrogen bonded dimers with an anti-disposition. This represents the third modification of carbamazepine that has been cryst...

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Crystal polymorphism in a carbamazepine derivative: oxcarbazepine.

Although crystal polymorphism of carbamazepine (CBZ), an anticonvulsant used to treat epilepsy, has been known for decades, the phenomenon has only recently been noted for its keto-derivative oxcarbazepine (OCB). Here it is demonstrated that OCB possesses at least three anhydrous polymorphs. Although all forms are morphologically similar, making differentiation between crystal modifications by ...

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The structure of potassium dichromate (P , Z = 4) consists of two layers parallel to (001), between which no crystallographic symmetry relation exists. These layers are nearly coincident with each other when rotated through 90° about c*. One question remained unanswered: do the crystals grow parallel to {001} with d(002) or d(001) layers? The pseudo-fourfold axis does not run parallel to a crys...

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ژورنال

عنوان ژورنال: Acta Crystallographica Section A Foundations and Advances

سال: 2014

ISSN: 2053-2733

DOI: 10.1107/s2053273314093383